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KMID : 0363620190400020119
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Journal of Korean Oriental Medicine
2019 Volume.40 No. 2 p.119 ~ p.132
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Effectiveness of comprehensive traditional Korean Medicine treatment on quality of life, anorexia and cachexia of cancer patients: Retrospective chart review
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Han Won-Ju
Lee Eun-Ji
Han Ga-Jin
Yoon Sang-Hoon
Han Ga-Jin
Leem Jung-Tae
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Abstract
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Purpose: This study was conducted to collect and analyze real world data to evaluate the effectiveness and safety of comprehensive traditional Korean Medicine treatment on quality of life, anorexia and cachexia of cancer patients.
Methods: We analyzed medical records of 62 cancer patients admitted to O-I Dang Korean Medicine Hospital from February 2018 to February 2019. The primary outcome was a change score in the Anorexia/Cachexia Subscale of Functional Assessment of Anorexia/Cachexia Therapy (FAACT). The secondary outcomes were Functional Assessment of Cancer Therapy-General (FACT-G), Trial Outcome Index(TOI) of FAACT, 11 point Pain Intensity Numeric Rating Score (11 PI-NRS) and Patient Global Impression of Change (PGIC) and adverse event.
Results: Cachexia and quality of life in cancer patients assessed by FAACT, increased by 5.59±14.83 (p=0.004) after treatment. PI-NRS was reduced by 2.10±1.81 (p<0.001) and TOI and FACT-G total scores were increased by 5.17±11.70 (p=0.001) and 3.59±10.94 (p=0.012), respectively. These results were also clinically meaningful assessed via minimal clinically important difference (MCID). There was no severe adverse event.
Conclusion: These findings suggest that comprehensive traditional Korean Medicine treatment might be effective and safe strategy for improving quality of life, anorexia, cachexia and pain of cancer patients. Further advanced studies with controlled group and more participants with rigorous design are needed to ensure these findings
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KEYWORD
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Anorexia, Cachexia, Neoplasm, Quality of life, Medicine, Korean Traditional, Retrospective studies
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